Table 1 Overall data of the patients (n = 60) and samples included in this study (n = 105).
Parameter | Value |
|---|---|
Patients Features | |
Men, n (%) | 51 (85) |
MSM, n (%) | 51/51 (100) |
Female (%) | 9 (15) |
Women with previous history of genital neoplasia, n (%) | 6/9 (67) |
Age (years), mean ± SD | 42 ± 13 |
HIV-positive, n (%) | 53 (88) |
CD4 (cells/mm3) sample collection, mean ± SD | 628 ± 278 |
Previous history of anal squamous cell carcinoma, n (%) | 1 (2) |
Pharmacologically immunosuppression, n (%) | 2 (3) |
Current or past smoking history, n (%) | 19/45 (42) |
Unknown history of smoking (missing data) | 15/60 (25) |
Anal HPV 16 positivity, n (%) | 28 (47) |
Anal HPV 18 positivity, n (%) | 18 (30) |
Other anal high-risk HPV*, n (%) | 49 (82) |
HPV negative/low-risk, n (%) | 7 (12) |
Samples Features | |
LAST Classification | |
Negative, n (%) | 10 (9.5) |
LSIL, n (%) | 63 (60) |
HSIL, n (%) | 32 (30.5) |
AIN Classification | |
Negative for dysplasia, n (%) | 27 (26) |
AIN1, n (%) | 46 (44) |
AIN2, n (%) | 14 (13) |
AIN3, n (%) | 18 (17) |
Samples Location | |
Anal, n (%) | 85 (81) |
Perianal, n (%) | 20 (19) |
