Table 4 The correlation between clinicopathological factor and c-MYC GCN gain with ddPCR in 64 CRC patients of cohort 2.
Total number of cases | c-MYC ddPCR (Tissue) | p-value | |||||
|---|---|---|---|---|---|---|---|
4 > GCN | 4 ≤ GCN | ||||||
Age | 60> | 39 | 37 | 61.7% | 2 | 50.0% | 0.643 |
60≤ | 25 | 23 | 38.3% | 2 | 50.0% | ||
Sex | Male | 23 | 22 | 36.7% | 1 | 25.0% | 0.638 |
Female | 41 | 38 | 63.3% | 3 | 75.0% | ||
Size | 5 cm> | 49 | 47 | 78.3% | 2 | 50.0% | 0.195 |
5 cm≤ | 15 | 13 | 21.7% | 2 | 50.0% | ||
Location | Ascending to descending colon | 17 | 14 | 23.3% | 3 | 75.0% | 0.023 |
Recto-sigmoid colon | 47 | 46 | 76.7% | 1 | 25.0% | ||
T stage | 1–2 | 17 | 16 | 26.7% | 1 | 25.0% | 0.942 |
3–4 | 47 | 44 | 73.3% | 3 | 75.0% | ||
N stage | 0 | 34 | 34 | 56.7% | 0 | 0.0% | 0.028 |
1–2 | 30 | 26 | 43.3% | 4 | 100.0% | ||
M stage | 0 | 62 | 58 | 96.7% | 4 | 100.0% | 0.711 |
1 | 2 | 2 | 3.3% | 0 | 0.0% | ||
Differentiation | Low grade | 56 | 54 | 90.0% | 2 | 50.0% | 0.019 |
High grade | 8 | 6 | 10.0% | 2 | 50.0% | ||
Lymphatic invasion | No | 44 | 43 | 71.7% | 1 | 25.0% | 0.051 |
Yes | 20 | 17 | 28.3% | 3 | 75.0% | ||
Venous invasion | No | 48 | 46 | 76.7% | 2 | 50.0% | 0.233 |
Yes | 16 | 14 | 23.3% | 2 | 50.0% | ||
Perineura invasion | No | 39 | 37 | 61.7% | 2 | 50.0% | 0.643 |
Yes | 25 | 23 | 38.3% | 2 | 50.0% | ||
Tumor border | Infiltrative | 14 | 14 | 23.3% | 0 | 0.0% | 0.274 |
Expensile | 50 | 46 | 76.7% | 4 | 100.0% | ||
Post-operative Chemotherapy | No | 56 | 52 | 86.7% | 4 | 100.0% | 0.435 |
Yes | 8 | 8 | 13.3% | 0 | 0.0% | ||
