Figure 3

Effect of MG132 on HMCs proliferation. Exposure to 30 mmol/L glucose activated the proliferation of HMCs, manifesting as an increase of the absorbance value of MTT. Both MG132 and deguelin treatment effectively reduced the proliferation of HMCs. CON: normal glucose medium containing 5.5 mmol/L glucose; HG: high glucose containing 30 mmol/L glucose; MG132: high glucose containing 30 mmol/L glucose with MG132; Deguelin: high glucose containing 30 mmol/L glucose with deguelin. *P < 0.05 vs. CON; #P < 0.05 vs. HG.