Table 1 Metabolic parameters in the different groups. The results shown are means ± SEM. NC: normal control group; DN: diabetic nephropathy group; MG132: diabetic nephropathy plus MG132 treatment group; Deguelin: diabetic nephropathy plus deguelin treatment group; BW: body weight; KW: kidney weight; KI: body weight/kidney weight ratio; SCr: serum creatinine; Glu: blood glucose; TG: triglyceride; TC: cholesterol. *P < 0.05 vs. NC; ^#P < 0.05 vs. DN.

527.96 ± 2.78

1.26 ± 0.27

2.39 ± 0.75

32 ± 3.15

5.47 ± 0.65

0.57 ± 0.11

1.21 ± 0.04

310.85 ± 1.49*

2.24 ± 0.25*

7.21 ± 0.64*

44 ± 2.60*

24.66 ± 1.54*

1.98 ± 0.42*

2.57 ± 0.15*

366.15 ± 2.71*

1.66 ± 0.51*

4.53 ± 0.73*

40 ± 2.25*

20.35 ± 2.83*

1.77 ± 0.44*

2.44 ± 0.21*

381.47 ± 1.71*

1.78 ± 0.49*

4.66 ± 0.54*

41 ± 1.93*

20.67 ± 1.84*

1.92 ± 0.37*

2.19 ± 0.30*

541.80 ± 2.92

1.41 ± 0.19

2.60 ± 0.58

34 ± 2.71

5.66 ± 0.49

0.52 ± 0.09

1.20 ± 0.12

270.66 ± 3.52*

2.99 ± 0.14*

11.05 ± 1.69*

57 ± 3.32*

27.48 ± 3.31*

2.26 ± 0.65*

3.00 ± 0.23*

398.69 ± 2.80*^#

1.87 ± 0.42*^#

4.69 ± 0.97*^#

46 ± 3.28*

18.48 ± 2.17*^#

2.00 ± 0.14*

2.61 ± 0.18*

425.1 ± 1.99*^#

1.87 ± 0.65*^#

4.40 ± 0.91*^#

44 ± 1.98*

16.62 ± 2.04*^#

1.97 ± 0.37*

2.74 ± 0.19*

547.13 ± 3.31

1.72 ± 0.66

2.88 ± 1.43

34 ± 2.64

5.81 ± 0.63

0.57 ± 0.28

1.22 ± 0.38

248.11 ± 4.48*

3.27 ± 0.51*

13.18 ± 2.79*

64 ± 2.19*

31.59 ± 1.90*

2.31 ± 0.41*

3.18 ± 0.25*

425.17 ± 2.52*^#

2.08 ± 0.32*^#

4.89 ± 1.53*^#

49 ± 3.33*

12.64 ± 1.34*^#

2.06 ± 0.06*

2.94 ± 0.46*

440.84 ± 2.22*^#

2.11 ± 0.35*^#

4.79 ± 1.08*^#

47 ± 3.08*

11.95 ± 1.73*^#

2.01 ± 0.48*

2.99 ± 0.17*