Figure 2

Morphology observation and correlation between miR-302a and target genes analyzed in HCC tissues. (A–D) The HE-stained HCC tissues in A (×200) and B (×400) showed a typical HCC morphology, and the adjacent tissues showed a normal liver cell morphology (C ×200 and D ×400). (E) The expression of miR-302a, MAP3K2 and PBX3 were detected in 10 HCC tissues and 10 adjacent tissues by qPCR (**P < 0.01). (F) Linear correlation was applied to analyze the correlation between the miR-302a and MAP3K2 or PBX3 mRNA expression levels (**P < 0.01). Statistical analysis was conducted using Student’s t-test and Fisher’s least significant difference (LSD) method of two-way analysis of variance (ANOVA).