Table 1 Clinical and demographic characteristics of the cases and controls.

From: Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity

 

ATDH group (n = 203)

No-ATDH group (n = 299)

P value

Age, years

38.58 ± 16.42

38.42 ± 16.81

0.913$

Age, years#

36, 25.5, 68

35, 26, 71

 

Female

108 (53.2)

146 (48.8)

0.336&

Ethnicity

  

0.072*,§

   Han

181 (89.2)

280 (93.6)

 

   Tibetan

13 (6.4)

13 (4.3)

 

   Yi

7 (3.4)

6 (2.0)

 

   Others

2 (1.0)

0 (0)

 

Smoker

57 (29.2)

77 (26.4)

0.489§

Alcohol abuse

25 (12.8)

33 (11.4)

0.641§

Height, centimeter

162.85 ± 7.42

164.98 ± 7.97

0.125$

Weight, kilogram

54.78 ± 9.89

54.94 ± 10.30

0.866$

Positive HBsAg

18 (9.4)

15 (5.0)

0.059§

  1. Data shown as mean ± standard deviation; #data shown as median, interquartile range, range; data shown as number of cases (frequency) §analyzed by chi-square test; $analyzed by independent sample t test. *P value was calculated between the Han and the other populations.
  2. ATDH: antituberculosis drug-induced hepatotoxicity.