Table 1 Serum biochemical parameters in L-PGDS flox/flox and aP2-Cre/L-PGDS flox/flox mice.

From: L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance

 

LFD

HFD

C

LKO

C

LKO

NEFA (μEq/L)

1283.3 ± 66.1

1254.8 ± 97.7

1332.0 ± 74.2

1849.8 ± 301.2

Total cholesterol (mg/dL)

135.0 ± 6.7

*112.8 ± 4.6

210.0 ± 3.9

*106.4 ± 3.9

LDL-cholesterol (mg/dL)

12.6 ± 1.9

9.0 ± 1.3

14.8 ± 2.3

8.2 ± 0.6

HDL-cholesterol (mg/dL)

79.8 ± 8.7

67.8 ± 2.8

87.2 ± 2.3

*57.6 ± 2.3

Total lipid (mg/dL)

451.5 ± 8.7

*369.2 ± 11.5

555.0 ± 13.7

*393.2 ± 22.9

Glucose (mg/dL)

115.8 ± 11.9

105.0 ± 8.9

164.2 ± 17.6

*132.4 ± 14.5

TG (mg/dL)

110.3 ± 6.8

114.8 ± 17.6

161.3 ± 13.3

*78.3 ± 5.6

  1. C and LKO mean control L-PGDS flox/flox and aP2-Cre/L-PGDS flox/flox mice (n = 5), respectively. Data are present as means ± S.E. *p < 0.01, vs. control (C).
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