Table 3 Variations of the expression of genes involved in citrate degradation and methyl-citrate pathway.

From: Metabolic adaptation of adherent-invasive Escherichia coli to exposure to bile salts

Name

Product

Gene size

RNA-seq values (minimal medium)

RNA-seq values (bile salts)

Fold change

Fold change

p value

(bp)

RPKM

RPKM

(Log2)

acnA

aconitate hydratase 1

2675

1824

2317

−1.3

−0.34

2.142E-01

acnB

aconitate hydratase 2

2597

11663

19016

−1.6

−0.70

2.362E-02

acs

acetyl-coenzyme A synthetase

1958

2188

837

2.6

1.39

1.897E-04

citC

Citrate-lyase ligase

1058

326

588

1.8

0.85

8.689E-04

citD

Citrate lyase acyl carrier protein

296

5

50

9.1

3.18

3.731E-10

citE

Citrate lyase β subunit

908

48

332

7.0

2.80

1.628E-17

citF

Citrate lyase α chain

1532

55

362

6.6

2.72

8.791E-16

citG

dephosphocoenzyme-A

878

32

183

5.6

2.49

5.951E-14

citT

Citrate carrier

1463

271

732

2.7

1.43

2.076E-09

citX

Holo-citrate lyase synthase

551

5

59

10.6

3.41

1.042E-13

ttdA

L-tartrate dehydratase subunit α

908

237

49

4.8

2.27

2.511E-13

ttdB

L-tartrate dehydratase subunit β

605

317

66

4.8

2.27

6.822E-12

ttdR

transcriptional activator

932

635

341

1.9

0.90

5.398E-04

ttdT

tartrate carrier

1463

724

312

2.3

1.21

1.002E-06

prpR

operon regulatory protein

1586

192

435

2.3

1.19

1.071E-04

prpB

Methylisocitrate lyase

890

131

3094

23.6

4.56

1.828E-37

prpC

2-methylcitrate synthase

1169

106

1313

12.3

3.62

3.179E-30

prpD

2-methylcitrate dehydratase

1451

66

609

9.3

3.21

2.654E-26

prpE

Propionate-CoA ligase

1886

80

786

9.8

3.30

5.999E-33

  1. 1Values shown in bold are significant.