Figure 10 | Scientific Reports

Figure 10

From: The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

Figure 10

Marked reduction of brain plaque load in TASD-41 APP transgenic mice following 30-days of intraperitoneal injections of PTI-777. 6 month old TASD-41 APP transgenic mice were injected daily with saline or PTI-777. Within 30 days, PTI-777 reduced % Aβ plaque load by 33.2% (p < 0.05) and plaque number (per sq. mm) by 55.6% (p < 0.01). **p < 0.05; ***p < 0.001, by Student’s t-test. Bars represent mean +/− SEM. n = 8 per group.

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