Figure 4

Gjd3^{3′UTR-IRES-CreEGFP/+} mice maintain cardiac mechanical function. (a) Representative M-mode tracing of a wild-type mouse at P42. (b) Representative M-mode tracing of a Gjd3^{3′UTR-IRES-CreEGFP/+} mouse at P42. Based on M-mode echocardiography on wild-type and Gjd3^{3′UTR-IRES-CreEGFP/+} mice (n = 8 in each group), the following parameters were calculated: (c) Heart Rate (HR) in Beats Per Minute (BPM) was calculated, (d) Ejection Fraction (EF) in percentage, (e) Fractional Shortening (FS) in percentage, and (f) Cardiac Output (CO) in milliliters per minute (ml/min). Black circles represent individual WT and Gjd3^{3′UTR-IRES-CreEGFP/+} mice used in the study. Blue bars and grey bars represent WT and Gjd3^{3′UTR-IRES-CreEGFP/+} mice, respectively. No statistically significant differences (p-value > 0.05; labeled as n.s. [not significant]) were observed between groups.