Table 2 Abundance, % change and credible regression slope change for lipid variables identified as undergoing the largest degrees of change with increasing altitude.

From: Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp

 

Carbon chain length: double bond

Mode of ion detection

LDN abundance (AU)

EBC abundance (AU)

Δ% LDN to EBC

Δ Slope (AU/km)

Lipids increasing with ascent

Triglyceride

52:3

Positive

30.1

45.0

53.9

1.59

Triglyceride

52:4

Positive

10.72

16.50

53.7

0.529

Oleic acid

18:1

Negative

36.0

54.6

27.1

2.349

Linoleic acid

18:2

Negative

17.83

23.39

23.7

0.828

Sphingomyelin

34:1

Positive

26.8

30.8

15.7

0.001

Palmitic acid

16:0

Negative

110.4

116.7

12.4

2.176

Lipids decreasing with ascent

Triglyceride

48:1

Positive

4.25

2.42

−43.1

−0.334

Phosphatidylcholine

46:2

Negative

11.8

8.7

−25.0

−0.597

Triglyceride

50:1

Positive

10.95

9.69

−8.43

−0.524