Figure 7

Effects of imiquimod on IAV-induced antibody titers in BALF. Antibody titers measured by multiplex antibody assays in naïve (control; PBS) or mice infected with Hk x-31 at 103 PFU/mouse, with daily intranasal treatments of imiquimod (50 µg) or vehicle control (PBS: DMSO; 1%), starting 1 day prior to infection up until day 2 with analysis occurring either at day 7 or day 14. Data are represented as mean ± SEM of n = 5–13 experiments. Data are expressed as picograms per milliliter (pg/ml), with statistical analysis conducted via a one-way ANOVA followed by Tukey’s post hoc test for multiple comparisons. * and ** indicates p < 0.05 and p < 0.01, respectively.