Figure 3

The fold change of RCT (A) and the major retinal vessel diameter (B) assessments. The fold changes of RCT and major retinal vessel diameters were reduced significantly after Dex, lGTE, and hGTE treatment in EAU mice. The reductions between different doses of GTE were statistically significant in EAU mice. However, the reduced fold changes of RCT and major retinal vessel diameters in Dex and lGTE treatment groups, but not hGTE-treated group, were still significantly higher than PBS + Water group. There were no differences between PBS induction groups treated with water, lGTE, and hGTE. The asterisk marked above each bar represents the statistical significance of comparison between EAU + Water group and the corresponding group. Data are also presented as mean ± SEM and analyzed by Mann–Whitney U test (*P < 0.05, **P < 0.01, ***P < 0.001, ns = no significance).