Figure 5 | Scientific Reports

Figure 5

From: Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication

Figure 5

IFN-γ inhibits KSHV lytic replication in a time- and dose-dependent manner. iSLK.219 cells were induced without or with Dox (0.2 μg/ml), and IFN-γ (0, 20, or 200 units/ml) was added into the culture at the indicated time. Infectious virus titer in the culture supernatant was determined at 72 hr post-induction and normalized to the medium-treated control. The means ± SEM of triplicated samples is plotted. One representative result is shown from 3 independent experiments. *P < 0.01 by one-way ANOVA Tukey method.

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