Table 1 Expression of cytokines, chemokines, and growth factors from co-cultures of tonsillar B and T cells.

From: Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication

Co-culture

IP-10

RANTES

IFN-γ

TNF-α

TNF-β

PDGF-AA

Infected

Uninfected

(unit: ng/ml§)

B

none

ND

0.1

0.4

ND

0.3

0.1

B

B

ND

2.0

2.9

0.2

1.0

0.1

none

T w/o PHA*

3.7

54.1

2.4

8.4

3.3

1.7

none

T w/PHA#

3.9

189.5

7.1

22.5

5.3

4.1

B

T w/o PHA

4.8

48.2

2.6

6.5

1.5

0.4

B

T w/PHA

6.7

190.5

12.8

38.8

7.3

6.9

  1. The mean of duplicated samples is shown.
  2. *T cells not stimulated with phytohaemagglutinin (PHA);
  3. #T cells stimulated with PHA for 6 hr prior to co-culture with B cells; ND, not detected.
  4. §Specific activity of each cytokine was not measured. For comparison, specific activities of recombinant proteins utilized in this study are provided. RANTES: 2 × 105 units/mg; IP-10, IFN-γ, TNFs, PDGF isotypes: 2 × 107 units/mg.
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