Table 1 Demographic, anthropometric and biochemical features of HC and NC subjects.
From: Faecal bacterial and short-chain fatty acids signature in hypercholesterolemia
HC | NC | p-value | q-value | |
|---|---|---|---|---|
Demographic features | ||||
N | 21 | 9 | ||
Sex | Male | Male | ||
Race | Caucasian | Caucasian | ||
Country | Spain | Spain | ||
Region | Catalonia | Catalonia | ||
Age (years) | 54.5 ± 7.5 | 43.67 ± 7.48 | 0.0024 | 0.0114 |
Anthropometric data | ||||
BMI (kg/m2) | 28.4 ± 2.8 | 26.18 ± 5.37 | 0.0315 | 0.0883 |
WHR | 0.96 ± 0.04 | 0.91 ± 0.04 | 0.0080 | 0.0281 |
Body fat percentage | 26 ± 4.7 | 25.2 ± 6.7 | 0.7483 | 0.7483 |
Biceps fold (mm) | 8.0 ± 2.3 | 7.26 ± 3.41 | 0.2264 | 0.3169 |
Triceps fold (mm) | 14.6 ± 4.7 | 15.5 ± 7.2 | 0.6248 | 0.6248 |
Subscapular fold (mm) | 22.3 ± 6.4 | 21.17 ± 8.5 | 0.7182 | 0.7483 |
Suprailiac fold (mm) | 15.5 ± 5.4 | 11.4 ± 4.7 | 0.0563 | 0.0985 |
Blood pressure (mmHg) | ||||
Systolic blood pressure | 134.4 ± 17.4 | 119.56 ± 12.21 | 0.0401 | 0.0899 |
Diastolic blood pressure | 88.4 ± 11.2 | 80.89 ± 9.92 | 0.0945 | 0.1469 |
Mean blood pressure | 106.1 ± 27.6 | 100.22 ± 10.4 | 0.0449 | 0.0899 |
Blood biochemistry | ||||
Glucose (mg/dL) | 109.22 ± 9.78 | 97.6 ± 7.0 | 0.0025 | 0.0175 |
Lactate (mg/dL) | 26.6 ± 9.5 | 22.2 ± 11.8 | 0.3444 | 0.4822 |
Uric acid (mg/dL) | 5.9 ± 1.4 | 4.4 ± 0.4 | 0.0002 | 0.0024 |
Lipids | ||||
Cholesterol (C) (mg/dL) | ||||
VLDL-C | 16.93 ± 11.23 | 8.61 ± 4.35 | 0.0503 | 0.0795 |
IDL-C | 10.77 ± 4.28 | 6.8 ± 2.35 | 0.0022 | 0.0055 |
LDL-C | 123.32 ± 22.08 | 89.48 ± 16.73 | <0.0001 | 0.0003 |
HDL-C | 51.61 ± 7.59 | 52.55 ± 9.13 | 0.8994 | 0.8994 |
Total-C | 202.62 ± 30.32 | 157.44 ± 24.14 | 0.0002 | 0.0009 |
Triglycerides (TG) (mg/dL) | ||||
VLDL-TG | 88.34 ± 58.2 | 47.06 ± 18.97 | 0.0503 | 0.0795 |
IDL-TG | 11.7 ± 3.47 | 8.31 ± 1.99 | 0.0027 | 0.0063 |
LDL-TG | 15.4 ± 4.78 | 9.57 ± 3.04 | 0.0003 | 0.0008 |
HDL-TG | 14.67 ± 4.91 | 12.32 ± 2.38 | 0.3722 | 0.4136 |
Total-TG | 130.12 ± 64.17 | 77.26 ± 21.46 | 0.0315 | 0.0676 |
Particle number (P) | ||||
VLDL-P (nmol/L) | 58.59 ± 40.55 | 30.35 ± 12.52 | 0.0563 | 0.0844 |
Large VLDL-P (nmol/L) | 1.8 ± 0.9 | 1.11 ± 0.5 | 0.0449 | 0.0795 |
Medium VLDL-P (nmol/L) | 8.7 ± 4.99 | 5.01 ± 1.75 | 0.0111 | 0.0208 |
Small VLDL-P (nmol/L) | 48.09 ± 34.96 | 24.23 ± 10.36 | 0.0627 | 0.0896 |
LDL-P (nmol/L) | 891.61 ± 161.53 | 637.23 ± 119.17 | <0.0001 | 0.0003 |
Large LDL-P (nmol/L) | 108.36 ± 24.97 | 79.65 ± 16.69 | 0.0005 | 0.0014 |
Medium LDL-P (nmol/L) | 324.09 ± 72.68 | 230.39 ± 53.33 | 0.0006 | 0.0017 |
Small LDL-P (nmol/L) | 459.16 ± 81.6 | 327.19 ± 58.95 | <0.0001 | 0.0003 |
HDL-P (μmol/L) | 29.14 ± 4.13 | 27.13 ± 3.33 | 0.2022 | 0.2426 |
Large HDL-P (μmol/L) | 0.19 ± 0.06 | 0.16 ± 0.05 | 0.2452 | 0.2829 |
Medium HDL-P (μmol/L) | 7.41 ± 2.25 | 8.51 ± 1.88 | 0.3375 | 0.375 |
Small HDL-P (μmol/L) | 21.54 ± 3.93 | 18.46 ± 2.1 | 0.02424 | 0.03463 |
Particle Diameter (Z) | ||||
VLDL-Z (nm) | 42.55 ± 0.56 | 42.8 ± 0.36 | 0.1623 | 0.2029 |
LDL-Z (nm) | 21 ± 0.2 | 21.02 ± 0.16 | 0.7558 | 0.7819 |
HDL-Z (nm) | 8.17 ± 0.06 | 8.22 ± 0.04 | 0.0387 | 0.05279 |
Other Parameters | ||||
Non-HDL-P (nmol/L) | 921.06 ± 167.78 | 640.45 ± 112.93 | <0.0001 | 0.0001 |
Total-P/HDL-P | 32.92 ± 5.72 | 24.59 ± 2.94 | <0.0001 | 0.0001 |
LDL-P/HDL-P | 30.93 ± 5.72 | 23.44 ± 3.06 | <0.0001 | 0.0001 |
Total-C/HDL-C | 3.97 ± 0.64 | 3.02 ± 0.3 | <0.0001 | 0.0001 |
ApoA1 (mg/dL) | 136.68 ± 22.07 | 142.49 ± 22.84 | 0.5291 | 0.5669 |
