Table 2 Affected Relatives and Proband Pc and Ps, The Faroe Islands.
From: Inheritance of Susceptibility to Malignant Blood Disorders
Affected Relatives (mean)/Pc | Affected Relatives Total (males, females) in Ps groups | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
m/m | f/m | m/f | f/f | Psm-PA | Psm-MA | Psf-PA | Psf-MA | Totals | ||
LPD/HL | 5.7 | 4.4 | 9.7 | 7.6 | OBS | 65(37, 28) | 25(13, 12) | 13(6, 7) | 18(12, 6) | 121(68, 53) |
EXP | 30(17, 13) | 30(17, 13) | 30(17, 13) | 30(17, 13) | 121(68, 53) | |||||
OBS/EXP (P) | 3(3, 3) | 0(0, 0) | −2(−2, 0) | −1(0, 0) | ||||||
LPD/NHL FL | 4.9 | 2.2 | 8.8 | 4.0 | OBS | 13(12, 1) | 19(12, 7) | 7(2, 5) | 25(18, 7) | 64(44, 20) |
EXP | 16(11, 5) | 16(11, 5) | 16(11, 5) | 16(11, 5) | 64(44, 20) | |||||
OBS/EXP (P) | 0(0, 0) | 0(0, 0) | −1(−2, 0) | 0(0, 0) | ||||||
LPD/NHL DLBCL | 4.7 | 3.9 | 7.6 | 6.3 | OBS | 59(32, 27) | 42(23, 19) | 39(24, 15) | 41(20, 21) | 181(99, 82) |
EXP | 45(25, 20) | 45(25, 20) | 45(25, 20) | 45(25, 20) | 181(99, 82) | |||||
OBS/EXP (P) | 1(0, 0) | 0(0, 0) | 0(0, 0) | 0(0, 0) | ||||||
LPD/NHL NOS | 5.9 | 3.7 | 7.5 | 4.7 | OBS | 28(19, 9) | 37(22, 15) | 39(23, 16) | 30(18, 12) | 134(82, 52) |
EXP | 34(21, 13) | 34(21, 13) | 34(21, 13) | 34(21, 13) | 134(82, 52) | |||||
OBS/EXP (P) | 0(0, 0) | 0(0, 0) | 0(0, 0) | 0(0, 0) | ||||||
LPD/MM | 5.8 | 4.3 | 9.5 | 7.0 | OBS | 102(63, 39) | 88(46, 42) | 46(23, 23) | 77(48, 29) | 313(180, 133) |
EXP | 78(45, 33) | 78(45, 33) | 78(45, 33) | 78(45, 33) | 313(180, 133) | |||||
OBS/EXP (P) | 2(2, 0) | 0(0, 0) | −3(−3, 0) | 0(0, 0) | ||||||
LPD/CLL | 5.0 | 3.2 | 7.0 | 4.5 | OBS | 82(53, 29) | 77(51, 26) | 43(19, 24) | 38(23, 15) | 240(146, 94) |
EXP | 60(37, 23) | 60(37, 23) | 60(37, 23) | 60(37, 23) | 240(146, 94) | |||||
OBS/EXP (P) | 2(2, 0) | 1(1, 0) | −1(−2, 0) | −2(−1, 0) | ||||||
MM/CLL | (Small sample size) | OBS | 21(14, 7) | 17(10, 7) | 13(9, 4) | 4(4, 0) | 55(37, 18) | |||
EXP | 14(9, 5) | 14(9, 5) | 14(9, 5) | 14(9, 5) | 55(37, 18) | |||||
CLL/CLL | (Small sample size) | OBS | 15(10, 5) | 14(7, 7) | 12(9, 3) | 10(4, 6) | 51(30, 21) | |||
EXP | 13(8, 5) | 13(8, 5) | 13(8, 5) | 13(8, 5) | 51(30, 21) | |||||
LPD/ALL | 3.5 | 1.6 | 5.8 | 2.7 | OBS | 19(15, 4) | 10(6, 4) | 7(3, 4) | 15(11, 4) | 51(35, 16) |
EXP | 13(9, 4) | 13(9, 4) | 13(9, 4) | 13(9, 4) | 51(35, 16) | |||||
OBS/EXP (P) | 0(0, 0) | 0(0, 0) | 0(−1, 0) | 0(0, 0) | ||||||
LPD/other LPD | (Small sample size) | OBS | 11(8, 3) | 4(2, 2) | 25(9, 16) | 12(5, 7) | 52(24, 28) | |||
EXP | 13(6, 7) | 13(6, 7) | 13(6, 7) | 13(6, 7) | 52(24, 28) | |||||
LPD/LPD | 5.2 | 3.6 | 7.7 | 5.4 | OBS | 382(239, 143) | 299(175, 124) | 219(111, 108) | 256(153, 103) | 1156(678, 478) |
EXP | 289(170, 119) | 289(170, 119) | 289(170, 119) | 289(170, 119) | 1156(678, 478) | |||||
OBS/EXP (P) | 3(3, 1) | 0(0, 0) | −3(−3, 0) | 0(0, 0) | ||||||
MPD/LPD | 4.0 | 2.7 | 5.9 | 4.0 | OBS | 85(60, 25) | 64(40, 24) | 25(7, 18) | 63(34, 29) | 237(141, 96) |
EXP | 59(34, 24) | 59(34, 24) | 59(34, 24) | 59(34, 24) | 237(141, 96) | |||||
OBS/EXP (P) | 3(3, 0) | 0(0, 0) | −3(−3, 0) | 0(0, 0) | ||||||
LPD/MPD | 3.2 | 2.4 | 4.7 | 3.6 | OBS | 91(54, 37) | 79(44, 35) | 50(21, 29) | 71(45, 26) | 291(164, 127) |
EXP | 73(41, 32) | 73(41, 32) | 73(41, 32) | 73(41, 32) | 291(164, 127) | |||||
OBS/EXP (P) | 1(1, 0) | 0(0, 0) | −2(−2, 0) | 0(0, 0) | ||||||
MPD/MPD | 2.8 | 1.7 | 4.2 | 2.5 | OBS | 95(66, 29) | 66(45, 21) | 28(10, 18) | 47(27, 20) | 236(148, 88) |
EXP | 59(37, 22) | 59(37, 22) | 59(37, 22) | 59(37, 22) | 236(148, 88) | |||||
OBS/EXP (P) | 3(3, 0) | 0(0, 0) | −3(−3, 0) | 0(0, 0) | ||||||
MPD/AML | 2.5 | 1.7 | 4.4 | 3.0 | OBS | 41(27, 14) | 32(19, 13) | 17(7, 10) | 28(17, 11) | 118(70, 48) |
EXP | 30(18, 12) | 30(18, 12) | 30(18, 12) | 30(18, 12) | 118(70, 48) | |||||
OBS/EXP (P) | 1(1, 0) | 0(0, 0) | −1(−2, 0) | 0(0, 0) | ||||||
MPD/CML | 3.4 | 2.4 | 6.2 | 4.4 | OBS | 21(15, 6) | 12(9, 3) | 8(1, 7) | 12(6, 6) | 53(31, 22) |
EXP | 13(8, 5) | 13(8, 5) | 13(8, 5) | 13(8, 5) | 53(31, 22) | |||||
OBS/EXP (P) | 1(1, 0) | 0(0, 0) | 0(−1, 0) | 0(0, 0) | ||||||
MPD/other MPD | 3.1 | 1.1 | 3.4 | 1.2 | OBS | 26(19, 7) | 16(13, 3) | 2(0, 2) | 2(2, 0) | 46(34, 12) |
EXP | 12(9, 3) | 12(9, 3) | 12(9, 3) | 12(9, 3) | 46(34, 12) | |||||
OBS/EXP (P) | 3(3, 1) | 0(0, 0) | −2(−2, 0) | −2(−1, 0) | ||||||
