Figure 2 | Scientific Reports

Figure 2

From: Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development

Figure 2

Proportion of variance explained in the subthalamic nucleus and lentiform nucleus volumes by the psychiatric PRS at five different P-value thresholds. Plots indicate the variance explained with estimated 95% confidence interval. The x-axis displays the five different upper thresholds of P-values for inclusion in the PRS. Results significant after multiple testing correction are indicated with an asterisk (*). (a) Subthalamic nucleus, full mixed-ancestral cohort, (b) Lentiform nucleus, full mixed-ancestral cohort, (c) Subthalamic nucleus, European sub-sample, (d) Lentiform nucleus, European sub-sample.

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