Table 3 Subgroup analysis of crude and adjusted hazard ratios (95% confidence intervals) of gallstone for renal stone according to age and sex in study I.

From: Bidirectional association between gallstones and renal stones: Two longitudinal follow-up studies using a national sample cohort

Characteristics

Renal stone

Crude

P-value

Adjusted†

P-value

Age <30 years old, men (n = 2,395)

  Gallstone

2.22 (1.10–4.48)

0.027*

2.23 (1.10–4.50)

0.026*

  Control

1.00

 

1.00

 

Age <30 years old, women (n = 3,605)

  Gallstone

2.68 (1.20–5.96)

0.016*

2.68 (1.20–5.96)

0.016*

  Control

1.00

 

1.00

 

Age ≥30 and <60 years old, men (n = 27,720)

  Gallstone

1.90 (1.62–2.22)

<0.001*

1.90 (1.62–2.23)

<0.001*

  Control

1.00

 

1.00

 

Age ≥30 and <60 years old, women (n = 27,830)

  Gallstone

2.30 (1.89–2.81)

<0.001*

2.31 (1.89–2.82)

<0.001*

  Control

1.00

 

1.00

 

Age ≥60 years old, men (n = 20,020)

  Gallstone

1.62 (1.27–2.06)

<0.001*

1.62 (1.27–2.06)

<0.001*

  Control

1.00

 

1.00

 

Age ≥60 years old, women (n = 21,985)

  Gallstone

1.78 (1.36–2.34)

<0.001*

1.78 (1.36–2.33)

<0.001*

  Control

1.00

 

1.00

 
  1. *Cox proportional hazard regression model, significance at P < 0.05.
  2. †Adjusted model for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia.
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