Table 1 Baseline characteristics.
Covariates | Total | Men | Women | P | Non-diabetic men | Diabetic men | P | Non-diabetic women | Diabetic women | P |
|---|---|---|---|---|---|---|---|---|---|---|
N | 35,379 | 14,072 | 21,307 | 12,506 | 1,566 | 19,947 | 1,360 | |||
Age (years) | 62.1 (7.5) | 61.9 (8.0) | 62.3 (7.2) | 0.306 | 62 (8) | 64 (6) | <0.001 | 62 (7) | 64 (6) | <0.001 |
Height (cm) | 156 (8) | 164 (6) | 151 (6) | <0.001 | 164 (6) | 163 (6) | <0.001 | 152 (6) | 151 (6) | <0.001 |
Body weight (kg) | 57.7 (10.2) | 64.7 (9.2) | 53.1 (8.0) | <0.001 | 64.4 (9.0) | 66.9 (10.2) | <0.001 | 52.9 (7.8) | 56.8 (9.7) | <0.001 |
BMI (kg/m2) | 23.5 (3.3) | 24.0 (3.0) | 23.2 (3.4) | <0.001 | 23.9 (2.9) | 25.0 (3.3) | <0.001 | 23.0 (3.3) | 25.0 (4.1) | <0.001 |
Waist circumference (cm) | 84.0 (8.9) | 85.3 (8.0) | 83.1 (9.3) | <0.001 | 85.0 (7.9) | 88.1 (8.6) | <0.001 | 82.8 (9.2) | 87.9 (10.3) | <0.001 |
Systolic blood pressure (mmHg) | 129 (17) | 130 (17) | 128 (18) | <0.001 | 130 (16) | 134 (17) | <0.001 | 127 (18) | 134 (17) | <0.001 |
Diastolic blood pressure (mmHg) | 77 (10) | 79 (10) | 75 (10) | <0.001 | 79 (10) | 78 (10) | 0.201 | 75 (10) | 76 (10) | <0.001 |
Glucose (mg/dL) | 97 (17) | 101 (18) | 95 (15) | <0.001 | 97 (10) | 135 (32) | <0.001 | 93 (9) | 130 (35) | <0.001 |
HbA1c (%) | 5.69 (0.55) | 5.70 (0.61) | 5.68 (0.51) | <0.05 | 5.56 (0.32) | 6.87 (0.98) | <0.001 | 5.59 (0.31) | 6.95 (1.03) | <0.001 |
TC (mg/dL) | 211 (33) | 204 (32) | 216 (32) | <0.001 | 204 (32) | 203 (33) | 0.082 | 216 (32) | 215 (34) | <0.05 |
LDL (mg/dL) | 127 (29) | 122 (29) | 131 (29) | <0.001 | 123 (29) | 121 (29) | <0.01 | 131 (29) | 130 (31) | 0.483 |
HDL (mg/dL) | 62 (15) | 58 (15) | 65 (15) | <0.001 | 58 (15) | 56 (15) | <0.001 | 65 (15) | 60 (15) | <0.001 |
Triglyceride (mg/dL) | 110 (57) | 121 (63) | 103 (51) | <0.001 | 119 (63) | 131 (68) | <0.001 | 102 (50) | 120 (58) | <0.001 |
AST (IU/L) | 24 (8) | 25 (9) | 23 (7) | <0.001 | 25 (9) | 26 (12) | 0.082 | 23 (7) | 25 (11) | <0.01 |
ALT (IU/L) | 22 (12) | 24 (13) | 20 (11) | <0.001 | 24 (13) | 28 (18) | <0.001 | 20 (10) | 25 (17) | <0.001 |
γ-GTP (IU/L) | 33 (37) | 45 (50) | 25 (22) | <0.001 | 44 (48) | 54 (65) | <0.001 | 24 (21) | 32 (35) | <0.001 |
Uric acid (mg/dL) | 5.25 (1.34) | 6.08 (1.29) | 4.70 (1.07) | <0.001 | 6.11 (1.28) | 5.86 (1.35) | <0.001 | 4.68 (1.06) | 4.94 (1.18) | <0.001 |
Creatinine (mg/dL) | 0.72 (0.18) | 0.85 (0.18) | 0.63 (0.13) | <0.001 | 0.85 (0.18) | 0.84 (0.21) | <0.001 | 0.63 (0.12) | 0.62 (0.13) | <0.001 |
eGFR (mL /min/1.73 m2) | 75 (15) | 74 (15) | 75 (15) | <0.001 | 74 (14) | 75 (17) | 0.149 | 75 (15) | 77 (18) | <0.01 |
Proteinuria (≧1+) (%) | 4.3 | 6.0 | 3.3 | <0.001 | 5.2 | 11.9 | <0.001 | 2.9 | 7.7 | <0.001 |
Diabetes mellitus (%) | 8.3 | 11.1 | 6.4 | <0.001 | ||||||
Hypertension (%) | 43.1 | 47.5 | 40.2 | <0.001 | 46.0 | 60.0 | <0.001 | 38.8 | 61.7 | <0.001 |
Dyslipidemia (%) | 53.6 | 50.2 | 55.7 | <0.001 | 49.2 | 58.2 | <0.001 | 54.7 | 70.8 | <0.001 |
Anti-hypertensive drugs (%) | 26.5 | 28.2 | 25.3 | <0.001 | 26.4 | 42.6 | <0.001 | 23.9 | 46.4 | <0.001 |
Lipid-lowering drugs (%) | 14.4 | 8.8 | 18 | <0.001 | 7.7 | 17.8 | <0.001 | 16.8 | 35.4 | <0.001 |
Anti-diabetic drugs (%) | 4.1 | 5.5 | 3.2 | <0.001 | 0.0 | 49.7 | <0.001 | 0.0 | 50.5 | <0.001 |
Current smoker (%) | 13.0 | 23.4 | 6.2 | <0.001 | 23.1 | 25.9 | <0.05 | 6.2 | 6.1 | 0.878 |
Alcohol drinking | ||||||||||
Every day (%) | 18.3 | 38.6 | 4.9 | 38.9 | 36.0 | 5.0 | 3.7 | |||
Sometimes (%) | 21.5 | 29.8 | 16.0 | <0.001 | 29.7 | 30.5 | 0.077 | 16.4 | 11.5 | <0.001 |
Almost none (%) | 60.2 | 70.2 | 84.0 | 31.4 | 33.5 | 78.6 | 84.8 | |||