Figure 5 | Scientific Reports

Figure 5

From: Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection

Figure 5

Modulation of MUC5B expression by Kaempferol administration. (A) Representative AB/PAS stained microscopy lung sections (100X) with insets (400X) to show immunohistochemically stained MUC5B in airway epithelium. Bar represents 200 μm. (B) Graph plot of MUC5B mRNA levels in lung samples from animals of each experimental group. Each bar represents the mean fold change in gene expression of 4 determinations using 2−ddCt method. Data were normalized by actin and compared with the result of the Pc(−) control group. (C) MUC5B protein levels as determined by western blot in lung samples from each experimental group. Each bar represents the mean +/− SD of 4 determinations normalized by Actin. Significance between quantifications were determined using Mann-Whitney. * indicates P = 0.0286. ns indicates no significance.

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