Table 3 Anticoagulant activity of the 6th international standard of Hp and Fractions A-D in global APTT and specific Xa, IIa and HCII IIa assays.
Sample | Plasma APTT | AT anti-IIa | AT anti-Xa | HCII anti-IIa |
|---|---|---|---|---|
Specific Activity – IU/mg (95% CL) | ||||
A | 22.7 (21.9–23.5) | 13.4 (12.7–14.1) | 23.2 (21.8–24.7) | 14.4 (13.2–15.6) |
B | 70.8 (68.4–73.4) | 57.4 (54.5–60.5) | 60.1 (56.4–64.0) | 54.3 (50.0–58.9) |
C | 22.8 (27.8–29.8) | 18.6 (17.7–19.6) | 23.8 (22.3–25.3) | 17.7 (16.2–19.2) |
D | 77.0 (74.4–79.8) | 72.9 (66.5–79.9) | 79.1 (74.2–84.3) | 63.0 (58.1–68.4) |
Hp | 209 (191–229) | 209 (196–223) | 214 (207–221) | 241 (223–261) |