Table 3 Anticoagulant activity of the 6th international standard of Hp and Fractions A-D in global APTT and specific Xa, IIa and HCII IIa assays.

From: By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans

Sample

Plasma APTT

AT anti-IIa

AT anti-Xa

HCII anti-IIa

Specific Activity – IU/mg (95% CL)

A

22.7

(21.9–23.5)

13.4

(12.7–14.1)

23.2

(21.8–24.7)

14.4

(13.2–15.6)

B

70.8

(68.4–73.4)

57.4

(54.5–60.5)

60.1

(56.4–64.0)

54.3

(50.0–58.9)

C

22.8

(27.8–29.8)

18.6

(17.7–19.6)

23.8

(22.3–25.3)

17.7

(16.2–19.2)

D

77.0

(74.4–79.8)

72.9

(66.5–79.9)

79.1

(74.2–84.3)

63.0

(58.1–68.4)

Hp

209

(191–229)

209

(196–223)

214

(207–221)

241

(223–261)