Table 2 Correlations between preoperative SII and clinicopathological characteristics in primary and validation cohort.

From: Prognostic Value of Preoperative Systemic Immune-Inflammation Index in Patients with Cervical Cancer

Clinical parameter

Primary Cohort

Validation Cohort

SII ≤ 475 (170)

SII > 475 (158)

χ2

P

SII ≤ 475 (47)

SII > 475 (83)

χ2

P

Age

  

0.22

0.641

  

2.93

0.087

   ≤45

86

84

  

21

50

  

   >45

84

74

  

26

33

  

Histological grade

  

3.08

0.215

  

4.19

0.123

   G1

22

14

  

5

7

  

   G2

77

64

  

34

48

  

   G3

71

80

  

8

28

  

Tumor size

  

32.59

<0.001

  

30.41

<0.001

   ≤4

119

61

  

43

35

  

   >4

51

97

  

4

48

  

Lymph node metastasis

  

0.10

0.747

  

0.91

0.341

   Negative

132

125

  

37

59

  

   Positive

38

33

  

10

24

  

Lymphovascular invasion

  

1.22

0.270

  

0.01

0.982

   No

146

142

  

39

69

  

   Yes

24

16

  

8

14

  

FIGO stage

  

1.62

0.445

  

2.37

0.305

   IA

42

42

  

16

18

  

   IB

87

87

  

22

46

  

   IIA

41

29

  

9

19

  

   TRL

  

37.77

<0.001

  

8.40

0.004

   TRL (−)

163

112

  

45

63

  

   TRL (+)

7

46

  

2

20

  

NLR

  

83.69

<0.001

  

52.19

<0.001

   NLR ≤ 2.4

132

43

  

44

23

  

   NLR>2.4

38

115

  

3

60

  

PLR

  

59.55

<0.001

  

26.55

<0.001

   PLR ≤ 118

106

32

  

35

23

  

   PLR > 118

64

126

  

12

60

  

MLR

  

16.42

<0.001

  

10.70

0.001

   MLR ≤ 0.26

124

81

  

26

22

  

   MLR>0.26

46

77

  

21

61

  
  1. SII: systemic immune-inflammation index; TRL: tumour-related leucocytosis; NLR: neutrophil lymphocyte ratio; PLR: platelet lymphocyte ratio; MLR: monocyte lymphocyte ratio.
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