Figure 1 | Scientific Reports

Figure 1

From: Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes

Figure 1

The octa-repeat region of the PrP RNA carries putative G-quadruplexes, which can be omitted by G-to-C substitutions. (a) Schematic representation of the introduced G-to-C-substitutions in the ΔG4 PrP octa-repeat mRNA to alter putative G-quadruplex motifs. (b) Native agarose gel electrophoresis shows oligomerization of wt and PrP octa-repeat mRNA.

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