Table 4 Antimicrobial activity spectrum of HR 1-17 (HRNR2656–2684)*.

From: Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives

Microbe

n

LD90 (µg/ml)

LD100 (µg/ml)

Conditions

Staphylococcus aureus ATCC 6538

2

>300

>300

pH 5.5, 1% TSB

Pseudomonas aeruginosa ATCC10145

2

0.075

0.3

pH 5.5, 0.25% glucose

Pseudomonas aeruginosa ATCC10145

1

0.59

18.75

pH 5.5, 1% TSB

Escherichia coli ATCC11775

1

>300

>300

pH 5.5, 1% TSB

Candida albicans ATCC 24433

2

1,18

9.38

pH 5.5, 0.25% glucose

Candida albicans ATCC 24433

1

18.8

150

pH 5.5, 1% TSB

Burkholderia cepacia ATCC 25416

1

>300

>300

pH 5.5, 0.25% glucose

  1. *AA-sequence: GRHGSGLGHSSSHGQHGSGSGRSSSRGPY. CFU were examined in 10 mM NaP at indicated pH in the presence or absence of additives. All data shown are representatives. n: number of experiments.
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