Table 2 Characteristics of the SNPs in the study.

From: Polymorphisms of cytokine genes and tuberculosis in two independent studies

Gene/SNPs

Chr.

SNP

Location in gene

Function*

MA

MAF

MA

MAF

HWE

Han

Han

Tibetan

Tibetan

Han

Tibetan

IL1B

2

rs1143634

exon5 (nonsynonymous)

IL1B levels

A

0.02

A

0.03

0.340

0.776

rs16944

5′FLANKING

IL1B expression, IL1B levels

A

0.48

G

0.42

0.999

0.976

rs1143623

5′FLANKING

TFBS

G

0.41

G

0.48

0.731

0.991

IL6

7

rs17147230

Unkonwn

TFBS

T

0.44

A

0.48

0.645

0.554

rs1800795

5′FLANKING

IL6 expression, IL6 levels

C

0.002

C

0.002

0.993

0.999

rs2069837

intron2

TFBS

C

0.17

C

0.26

0.366

0.118

TNF

6

rs1799964

5′FLANKING

TNF expression, TNF levels

C

0.17

C

0.22

0.986

0.075

rs1800630

5′FLANKING

TNF expression, TFBS, TNF-alpha levels

A

0.16

A

0.18

0.841

0.024

rs1799724

5′FLANKING

TNF expression, TFBS, TNF-alpha levels

C

0.14

C

0.16

0.951

0.989

rs1800629

5′FLANKING

TNF expression, TNF-alpha levels

A

0.07

A

0.02

0.869

0.092

rs361525

5′FLANKING

TNF expression, TNF-alpha levels

A

0.02

A

0.04

0.281

0.686

  1. Abbreviation: SNP, single nucleotide polymorphism; MA, minor allele; MAF, minor allele frequency; HWE, Hardy Weinberg equilibrium; TFBS, transcription factor binding sites; Chr. chromosome.
  2. *Function of each SNP was reported by previous studies and/or predicted from the NIH FuncPred website (https://snpinfo.niehs.nih.gov/snpinfo/snpfunc.html).
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