Table 4 Association between genotype of cytokine genes and TB in the two populations.
From: Polymorphisms of cytokine genes and tuberculosis in two independent studies
Gene/SNPs | Han population | Tibetan population | ||
|---|---|---|---|---|
P # | OR# (95% CI) | P # | OR# (95% CI) | |
IL1B | ||||
rs1143634 | ||||
Dominant model | 0.130 | 1.61 (0.87–2.97) | 0.154 | 1.40 (0.88–2.21) |
Recessive model | — |  | — |  |
rs16944 | ||||
Dominant model | 0.042 | 0.78 (0.61–0.99) | 0.383 | 0.89 (0.69–1.56) |
Recessive model | 0.098 | 0.79 (0.59–1.05) | 0.660 | 0.95 (0.73–1.22) |
rs1143623 | ||||
Dominant model | 0.414 | 1.11 (0.87–1.40) | 0.508 | 1.09 (0.84–1.41) |
Recessive model | 0.123 | 1.26 (0.94–1.68) | 0.186 | 1.19 (0.92–1.55) |
IL6 | ||||
rs17147230 | ||||
Dominant model | 0.193 | 1.20 (0.91–1.59) | 0.934 | 0.99 (0.77–1.27) |
Recessive model | 0.725 | 1.04 (0.82–1.33) | 0.128 | 0.81 (0.62–1.06) |
rs1800795 | ||||
Dominant model | 0.161 | 0.32 (0.06–1.58) | 0.121 | 3.47 (0.72–16.79) |
Recessive model | — |  | — |  |
rs2069837 | ||||
Dominant model | 0.044 | 0.78 (0.62–0.99) | 0.820 | 1.03 (0.82–1.29) |
Recessive model | 0.462 | 0.82 (0.48–1.40) | 0.621 | 0.90 (0.60–1.36) |
TNF | ||||
rs1799964 | ||||
Dominant model | 0.017 | 1.33 (1.05–1.68) | 0.004 | 1.40 (1.11–1.76) |
Recessive model | 0.158 | 1.53 (0.85–2.74) | 0.627 | 1.12 (0.72–1.74) |
rs1800630 | ||||
Dominant model | 0.002 | 1.46 (1.15–1.85) | 0.017 | 1.34 (1.05–1.70) |
Recessive model | 0.652 | 1.13 (0.67–1.88) | 0.421 | 1.30 (0.69–2.46) |
rs1799724 | ||||
Dominant model | 0.686 | 0.95 (0.74–1.22) | <0.001 | 1.65 (1.30–2.10) |
Recessive model | 0.263 | 0.63 (0.28–1.41) | 0.003 | 2.49 (1.37–4.50) |
rs1800629 | ||||
Dominant model | 0.528 | 0.90 (0.66–1.24) | 0.038 | 0.59 (0.36–0.97) |
Recessive model | 0.964 | 0.96 (0.19–4.80) | — |  |
rs361525 | ||||
Dominant model | 0.899 | 1.04 (0.58–1.85) | 0.727 | 1.07 (0.72–1.61) |
Recessive model | 0.973 | 0.95 (0.06–15.31) | 0.982 | 0.98 (0.14–6.97) |
