Table 3 Univariate and Multivariate Cox proportional hazards model predictors of overall survival in clear cell RCC.
From: Syntaxin 6: A novel predictive and prognostic biomarker in papillary renal cell carcinoma
Variable | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
HR | 95% CI | p-Value | HR | 95% CI | p-Value | ||
Syntaxin 6 | Low (Reference) High | 1.326 | 0.965-1.822 | 0.082 | ā | ā | ā |
Age | ā¤65 (Reference) >65 | 1.590 | 1.181-2.140 | 0.002 | 1.782 | 1.314-2.418 | <0.0001 |
Gender | Male (Reference) Female | 0.988 | 0.725-1.346 | 0.938 | ā | ā | ā |
Race | White (Reference) Other | 1.128 | 0.554-2.298 | 0.740 | ā | ā | ā |
Grade | 1-2 (Reference) 3,4 | 2.521 | 1.795-3.542 | <0.0001 | 1.505 | 1.037-2.184 | 0.032 |
Pathologic Stage | I (Reference) II III IV | 1.300 2.517 5.416 | 0.701-2.413 1.679-3.775 3.708-7.909 | 0.405 <0.0001 <0.0001 | 1.355 2.060 4.848 | 0.727-2.524 1.346-3.153 3.197-7.351 | 0.339 0.001 <0.0001 |
