Table 5 Performance of the array in detecting resistance to 8 anti-tuberculosis drugs.

From: A new oligonucleotide array for the detection of multidrug and extensively drug-resistance tuberculosis

Drugs

Parameter

No. of isolates (R/S)

Sensitivity (%) [95% CI]

Specificity (%) [95% CI]

Rifampicin

160/16

98.8 (95.6–99.9)

93.8 (69.8–99.8)

Isoniazid

160/16

91.3 (85.8–95.1)

100.0 (79.4–100)

Ethambutol

116/60

79.3 (70.8–86.3)

80.0 (67.7–89.2)

Streptomycin

94/82

64.9 (54.4–74.5)

93.9 (86.3–98.0)

Ofloxacin

81/95

95.1 (87.8–98.6)

98.9 (94.3–100)

Kanamycin

72/104

100.0 (95.0–100)

98.1 (93.2–99.8)

Amikacin

56/120

98.2 (90.5–100)

98.3 (94.1–99.8)

Capreomycin

40/136

90.0 (76.3–97.2)

84.6 (77.4–90.2)

  1. CI, confidence interval; R, resistance; S, susceptible.
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