Figure 4
From: Machine learning-powered antibiotics phenotypic drug discovery
Identification of MoA for new antibacterial compound classes. Structures of the compound series 1. Indicated left of the structure is the quality of the fingerprint. Fingerprint quality: “Clear”: At least one parameter with >10 fold change in >85% of the individual datapoints at 4-fold LOED. “Weak”, no single parameter with consistent change required for classification as “clear”, but visual inspection reveals presence of a systematic weaker fingerprint including >5 parameters.
