Figure 1 | Scientific Reports

Figure 1

From: p38α deficiency restrains liver regeneration after partial hepatectomy triggering oxidative stress and liver injury

Figure 1

Effect of liver specific p38α MAPK deficiency on cyclin mRNA expression after partial hepatectomy. (A) Real-time PCR analysis of the mRNA relative expression for Cyclin D1, A1, Cdc25b, B1 and B2 in liver 72 hours after hepatectomy (PHx). Data (mean and SD) are shown as fold increase in mRNA level compared to the control and were normalized by TATA-binding protein mRNA. (B) Representative western blot images and densitometries for cyclin D1 and cyclin B1 in nuclear extracts of livers from sham wild type and p38α knockout mice and at 72 hours after PHx. TBP was used as a loading control. *P < 0.05; **P < 0.01. WT, wild type mice; KO, p38α knockout mice; PHx, partial hepatectomy.

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