Figure 5

p38α MAPK deficiency triggers oxidative stress and liver injury after partial hepatectomy. (A) Hepatic levels of reduced (GSH) and oxidized (GSSG) glutathione. (B) Plasma activities of alanine aminotransferase (ALT), (C) aspartate aminotransferase (AST) and (D) lactate dehydrogenase and (E) plasma protein levels in wild type and p38α knockout mouse after partial hepatectomy. Data are shown as mean and SD. *P < 0.05 **P < 0.01. WT wild type mice; KO p38α knockout mice; PHx partial hepatectomy.