Figure 3 | Scientific Reports

Figure 3

From: Enriched environment alleviates stress-induced dry-eye through the BDNF axis

Figure 3

Bdnf expressions decreases in response to stress and increases in response to housing in an enriched environment. (a) In the hippocampus (HC), Bdnf expression decreased in response to stress (n = 3; *P < 0.05 by Student’s t-test). (b) In the HC and Hypothalamus (HT), Bdnf expression increased in response to an enriched environment (EE; n = 4; **P < 0.01, *P < 0.05 by Student’s t-test). (c) EE housing restored the previously-observed stress-dependent decline in Bdnf expression (n = 3; **P < 0.01, *P < 0.05 by one-way ANOVA with post-hoc Tukey’s test).

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