Table 3 Toxicity profile (by maximum grade).

From: Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer: a prospective study on toxicity and quality of life

Toxicity

Acute

Medium-term

N

%

N

%

Skina (N = 121)

Grade 1

74

61.2

28

23.1

Grade 2

40

33.1

1

0.8

Grade 3

2

1.7

1

0.8

Unknown

1

0.8

All grades

116

95.9

31

25.6

Fibrosisa (N = 121)

Grade 1

N/A

N/A

27

22.3

Grade 2

N/A

N/A

8

6.6

Unknown

N/A

N/A

1

0.8

All grades

N/A

N/A

36

29.8

Esophageal b (N = 114)

Grade 1

59

51.8

2

1.8

Grade 2

9

7.9

0

0

All grades

68

59.6

2

1.8

  1. Footnotes:
  2. aPer breast.
  3. bPer patient.
  4. *Skin toxicity is defined by the following terms: radiodermatitis, ulceration-necrosis, telangiectasia, atrophy, hyperpigmentation, hypopigmentation.
  5. **Late skin toxicity and fibrosis: we only considered events that had not been reported as acute toxicities or whose grade increased.
  6. Abbreviations: N/A = non-applicable.