Figure 1
From: Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice
Increased spleen and lymph node size in IL-17RA KO/lpr mice. (A) Spleens and cervical lymph nodes from 30 week old B6/lpr (left and top) and IL-17RA KO/lpr (right and bottom). (B) Total number of splenocytes (all live cells in spleen) at different ages. Bars depict wild type B6 (grey stripe), wild type IL-17RA KO (open stripe), B6/lpr (black), and IL-17RA.KO/lpr (open) mice at 10, 20 and 30 weeks of age. Mean and SEM are shown for n = 3–21 mice per group; *p < 0.05; **p < 0.01.
