Table 1 The IC50 values of ZINC24469384, ZINC08671161, ZINC48302525 and ZINC080113624 against different cancer and normal cell lines.

From: A novel benzamine lead compound of histone deacetylase inhibitor ZINC24469384 can suppresses HepG2 cells proliferation by upregulating NR1H4

Chemicals

HepG2

IC50(μM)

Hep3B

L02

A549

A2780

SGC7901

ZINC24469384

39 ± 5

49 ± 4

79 ± 3

53 ± 1

56 ± 4

69 ± 4

ZINC08671161

124 ± 17

151 ± 20

70 ± 3

154 ± 31

103 ± 5

>300

ZINC48302525

115 ± 5

232 ± 26

152 ± 22

258 ± 22

128.4 ± 8

>300

ZINC080113624

 

>300

Back to article page