Table 2 Comparison between the iNPH+/NTG+ and iNPH+/NTG− groups.

From: Optic disc cupping characteristics of normal pressure hydrocephalus patients with normal-tension glaucoma

Variables

non-NTG-iNPH

NTG-iNPH

p value‡

ICP (mmHg)

Mean ± SD

8.3 ± 1.4

10.8 ± 2.9

†<0.005***

[range]

5.9–9.9

5.7–14.1

 

MMSE prior to CSF tapping

Mean ± SD

22.33 ± 5.29

23.27 ± 4.73

NS***

[range]

12–30

16–28

 

MMSE after CSF tapping

Mean ± SD

24.22 ± 5.22

25.09 ± 4.09

NS***

[range]

18–30

16–30

 

Cognitive function (improved: no improvement) (n)

6:3

6:5

NS***

Gait disturbance (improved: no improvement) (n)

8:1

6:5

NS***

P-tau

  

NS***

Mean ± SD

40.9 ± 12.7

51.8 ± 25.3

 

[range]

27.8–63.2

32.3–109.0

 
  1. ‡Two groups compared using the t-test.
  2. †Statistically significant difference between the non-NTG-iNPH and NTG-iNPH groups (Steel-Dwass test).
  3. SD, standard deviation; ICP, intra cranial pressure; MMSE, Mini-Mental State Examination; CSF, cerebrospinal fluid; p-tau, tau protein; NTG, normal-tension glaucoma: iNPH, idiopathic normal tension hydrocephalus.
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