Figure 5
From: The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface
The I65M NEMO mutant mimics the open bun conformation. NEMO-EEAA (blue), NEMO-I65M (orange) and NEMO in the IKKβ complex (PDB: 3BRV, grey). (a) Proteins displayed as transparent ribbons encompassing residues 55–81 are superimposed on chain A. The angle between the helix axis for NEMO-EEAA and NEMO-I65M is shown by the arrows in the region 57–77: 5.66 degrees. (b) Effect of the Met/Ile mutation (shown as sticks).
