Figure 4 | Scientific Reports

Figure 4

From: CD271-selected mesenchymal stem cells from adipose tissue enhance cartilage repair and are less angiogenic than plastic adherent mesenchymal stem cells

Figure 4

The effects of conditioned medium from PA MSCs and CD271+ MSCs on EA.hy926 endothelial cell migration. (A) Live cell imaging was used to determine the rate of endothelial cell migration in scratch assays in PA MSC conditioned medium versus CD271+ MSC conditioned medium and non-conditioned control medium. As shown, there was a significant increase in endothelial migration in PA MSC conditioned medium versus both other groups, with CD271+ MSC conditioned medium proving no greater than control conditions. (B) This difference in endothelial cell migration was further evidenced by the rate of wound closure in these scratch assays, where the rate of closure in CD271+ MSC conditioned medium was significantly slower compared with the PA MSC conditioned medium (p < 0.01). Data shown are means ± SEMs.

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