Figure 5
Median nerve-based CD model. (A) The median nerve is transected and denervated for a given period (e.g. 8 weeks in our study). To prevent nerve regeneration across the transected median nerve throughout the CD period, ~1.5 cm of the proximal median nerve stump is resected and the distal stump is sutured to the biceps brevis. (B) In order, to isolate the effects of chronic denervation from chronic axotomy injury, the distal, denervated median nerve stump is co-apted to a the freshly transected ulnar nerve at the time of repair. (C) In-vivo presentation of the ulnar to median nerve transfer at the time of repair.
