Table 3 Multivariate logistic regression analysis to determine the factors associated with center-involved DME in 209 diabetic patients.
From: Anti-Hexokinase 1 Antibody as a Novel Serum Biomarker of a Subgroup of Diabetic Macular Edema
Characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (CI 95%) | P value | OR (CI 95%) | P value | |
Age | 1.008 (0.985–1.032) | 0.502 | — | — |
Gender | 1.343 (0.741–2.432) | 0.331 | — | — |
Diabetes duration | 0.977 (0.946–1.010) | 0.164 | — | — |
Mean arterial blood pressure | 1.029 (1.004–1.055) | 0.024 | 1.031 (1.001–1.061) | 0.039 |
HbA1c | 0.987 (0.821–1.186) | 0.885 | — | — |
Systemic hypertension | 1.250 (0.701–2.230) | 0.450 | — | — |
Dyslipidaemia | 0.961 (0.551–1.675) | 0.888 | — | — |
Phakic in both eyes | 1.543 (0.834–2.855) | 0.167 | — | — |
PDR in either eye | 2.710 (1.288–5.702) | 0.009 | 0.787 (0.273–2.266) | 0.657 |
Prior PRP in either eye | 5.663 (2.695–11.902) | <0.001 | 8.011 (2.828–22.697) | <0.001 |
Titer of anti-fumarase IgG | 2077.4 (48.6–88862.3) | <0.001 | 266.7 (3.0–23470.4) | 0.014 |
Titer of anti-hexokinase 1 IgG | 210.3 (16.5–2679.3) | <0.001 | 183.8 (8.7–3889.9) | <0.001 |
