Table 4 Multivariate logistic regression analysis to determine the factors associated with center-involved DME in 163 DR participants.
From: Anti-Hexokinase 1 Antibody as a Novel Serum Biomarker of a Subgroup of Diabetic Macular Edema
Characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (CI 95%) | P value | OR (CI 95%) | P value | |
Age | 1.010 (0.984–1.036) | 0.452 | — | — |
Gender | 1.416 (0.727–2.758) | 0.307 | — | — |
Diabetes duration | 0.953 (0.917–0.990) | 0.014 | 0.936 (0.895–0.980) | 0.005 |
Mean arterial blood pressure | 1.018 (0.993–1.045) | 0.164 | — | — |
HbA1c | 0.961 (0.788–1.172) | 0.693 | — | — |
Systemic hypertension | 1.058 (0.554–2.019) | 0.865 | — | — |
Dyslipidaemia | 0.996 (0.538–1.846) | 0.991 | — | — |
Phakic in both eyes | 1.061 (0.549–2.050) | 0.861 | — | — |
PDR in either eye | 1.597 (0.747–3.414) | 0.227 | — | — |
Prior PRP in either eye | 3.378 (1.583–7.208) | 0.002 | 7.224 (2.712–19.240) | <0.001 |
Titer of anti-fumarase IgG | 970.3 (15.4–61153.5) | 0.001 | 143.5 (1.2–17185.2) | 0.042 |
Titer of anti-hexokinase 1 IgG | 100.1 (6.7–1507.3) | <0.001 | 41.3 (1.8–941.3) | 0.020 |
