Table 2 Results of the pathway analysis of the T2DM network. In blue the pathways in common between the AD and T2DM networks.
p value | q value | Pathway | Source |
|---|---|---|---|
3.74E-15 | 6.64E-13 | Thyroid hormone signaling pathway - Homo sapiens (human) | KEGG |
1.17E-13 | 1.38E-11 | mechanism of gene regulation by peroxisome proliferators via ppara | BioCarta |
2.79E-11 | 2.29E-09 | FoxO signaling pathway - Homo sapiens (human) | KEGG |
1.28E-10 | 8.49E-09 | Macroautophagy | Reactome |
1.44E-10 | 9.05E-09 | NOTCH1 Intracellular Domain Regulates Transcription | Reactome |
3.31E-09 | 1.14E-07 | Beta-catenin phosphorylation cascade | Reactome |
4.50E-09 | 1.41E-07 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | Reactome |
6.66E-09 | 1.97E-07 | Circadian Clock | Reactome |
1.15E-08 | 2.98E-07 | Signaling by Interleukins | Reactome |
1.71E-08 | 4.05E-07 | Circadian rhythm - Homo sapiens (human) | KEGG |
2.04E-08 | 4.17E-07 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | Reactome |
2.47E-08 | 4.77E-07 | AMPK signaling pathway - Homo sapiens (human) | KEGG |
3.91E-08 | 7.06E-07 | IRS-mediated signalling | Reactome |
5.72E-08 | 9.46E-07 | Insulin receptor signalling cascade | Reactome |
2.19E-07 | 2.72E-06 | PI3K-Akt signaling pathway - Homo sapiens (human) | KEGG |
3.70E-07 | 4.19E-06 | Signaling by Wnt | Reactome |
9.83E-07 | 9.35E-06 | Signaling by NOTCH | Reactome |
2.77E-06 | 2.46E-05 | Signaling by Leptin | Reactome |
4.19E-06 | 3.46E-05 | Adipocytokine signaling pathway - Homo sapiens (human) | KEGG |
4.89E-06 | 3.88E-05 | Fatty acid, triacylglycerol, and ketone body metabolism | Reactome |
2.94E-05 | 0.000165458 | Sphingolipid signaling pathway - Homo sapiens (human) | KEGG |
0.000475166 | 0.001648377 | Wnt signaling pathway - Homo sapiens (human) | KEGG |
0.000531621 | 0.001820503 | mTOR signalling | Reactome |
0.001563324 | 0.004637717 | Cellular Senescence | Reactome |
0.001694211 | 0.004998158 | Neurotrophin signaling pathway - Homo sapiens (human) | KEGG |
0.003142557 | 0.008559651 | EPH-Ephrin signaling | Reactome |
0.004303806 | 0.011317415 | Interleukin-6 signaling | Reactome |
0.006542263 | 0.015980527 | Insulin signaling pathway - Homo sapiens (human) | KEGG |
0.008386082 | 0.019505104 | Prolactin receptor signaling | Reactome |
