Figure 3 | Scientific Reports

Figure 3

From: Dysfunctional high-density lipoprotein activates toll-like receptors via serum amyloid A in vascular smooth muscle cells

Figure 3

MCP-1 mRNA expression and protein secretion in rVSMC and THP-1 macrophage-like cell upon receptor agonists and antagonists. (A,C) MCP-1 mRNA expression and (B,D–F) MCP-1 protein secretion in (A–D) rVMSC or (E,F) THP-1 macrophage-like cells. RhSAA (1 µg/ml), BzATP (100 µmol/l), HKSA (107 cells/ml), LPS (1 µg/ml), KN-62 (10 µmol/l), OxPAPC (30 µg/ml), CU-CPT22 (10 µmol/l), CLI-095 (10 µmol/l). Data are presented as means ± SEM. (A,B,E,F) *p < 0.05 compared to control (ctrl.) or (C,D) compared to SAA-stimulation.

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