Figure 1

Comparison between the evolutionary age of mouse genes in our knockout dataset (all essential and non-essential genes, left column), the evolutionary age of all genes in the mouse genome including knockout genes (middle column) and the evolutionary age of all genes in the mouse genome excluding the knockout genes (right column). The numbers at the top of the chart indicate gene age in millions of years (MYr). Here, 25 MYr is the youngest taxonomic group, plotted at the bottom of each chart, and 1215 MYr is the oldest taxonomic group, plotted at the top of each chart. The ages, corresponding names of the taxonomic groups, and associated colours on the bar charts are 25= Murinae (blue), 77= Rodentia (red), 78 = Sciurognathi (green), 86 = Glires (purple), 92 = Euarchontoglires (turquoise), 104 = Eutheria (orange), 162 = Theria (dark blue), 167 = Mammalia (red), 296 = Amniota (green), 371 = Tetrapoda (purple), 400 = Euteleostomi (turquoise), 414 = Sarcopterygii (orange), 535 = Vertebrata (blue), 722 = Chordata (pink), 937 = Bilateria (green), 1215 = Opisthokonta (purple).