Table 4 Univariate and multivariate analyses of disease-free survival in breast cancer patients.

From: Elevated red cell distribution width to platelet count ratio predicts poor prognosis in patients with breast cancer

Characteristics

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Age (years)

<50

1

0.08

  

≥50

0.46 (0.19–1.09)

   

ER

Negative

1

0.29

  

Positive

0.65 (0.29–1.45)

   

Tumour size

<20 mm

1

0.00057

1

0.0014

≥20 mm

4.14 (1.84–9.30)

 

4.31 (1.76–10.53)

 

NG

1

1

0.029

1

0.17

2, 3

2.62 (1.10–6.25)

 

1.93 (0.76–4.93)

 

HER2

Negative

1

0.71

  

Positive

0.79 (0.24–2.65)

   

PgR

Negative

1

0.86

  

Positive

0.94 (0.43–2.03)

   

LN

Negative

1

0.09

  

Positive

1.97 (0.89–4.34)

   

PDW/P

<0.59

1

 

1

0.37

≥0.59

2.23 (1.02–4.85)

0.044

1.56 (0.59–4.13)

 

RDW

<13.7

1

0.26

  

≥13.7

1.58 (0.72–3.50)

   

RPR

<0.71

1

 

1

0.048

≥0.71

2.21 (1.10–4.81)

0.046

2.79 (1.01–7.69)

 
  1. Abbreviations: NG, nuclear grade; LN, lymph node involvement; ER, oestrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2; PDW/P, platelet distribution width to platelet count ratio; RDW, red cell distribution width; RPR, red cell distribution width to platelet count ratio; CI, confidence interval.
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