Table 3 GSEA analysis.
Name | Size | ES | NES | p-value | Adjusted p-value |
|---|---|---|---|---|---|
(A) Pathways enriched in AR 100 motor neuron | |||||
KEGG ECM receptor interaction | 75 | 0.680 | 2.364 | 0 | 0 |
KEGG cell cycle | 111 | 0.628 | 2.348 | 0 | 0 |
KEGG focal adhesion | 180 | 0.570 | 2.260 | 0 | 0 |
KEGG DNA replication | 32 | 0.682 | 2.066 | 0 | 0 |
KEGG small cell lung cancer | 79 | 0.576 | 1.989 | 0 | 0.002 |
KEGG p53 signalling pathway | 60 | 0.577 | 1.975 | 0 | 0.002 |
KEGG regulation of actin cytoskeleton | 187 | 0.478 | 1.883 | 0 | 0.008 |
KEGG pathways in cancer | 305 | 0.455 | 1.883 | 0 | 0.007 |
KEGG lysosome | 109 | 0.490 | 1.817 | 0 | 0.015 |
KEGG lysine degradation | 42 | 0.548 | 1.742 | 0.002 | 0.031 |
KEGG basal cell carcinoma | 54 | 0.518 | 1.699 | 0.003 | 0.045 |
BioCarta GSK3 pathway | 27 | 0.676 | 1.942 | 0.002 | 0.028 |
BioCarta cell cycle pathway | 21 | 0.696 | 1.899 | 0 | 0.027 |
BioCarta G1 pathway | 26 | 0.660 | 1.885 | 0 | 0.021 |
BioCarta integrin pathway | 38 | 0.598 | 1.825 | 0 | 0.042 |
BioCarta ALK pathway | 35 | 0.598 | 1.825 | 0.002 | 0.034 |
BioCarta p38 MAPK pathway | 38 | 0.594 | 1.819 | 0 | 0.030 |
BioCarta HIV nef pathway | 53 | 0.545 | 1.806 | 0 | 0.030 |
(B) Pathways decreased in AR 100 motor neurons | |||||
KEGG neuroactive ligand receptor interaction | 22 | −0.427 | −1.936 | 0 | 0.007 |
KEGG regulation of autophagy | 24 | −0.493 | −1.504 | 0.038 | 0.302 |
KEGG autoimmune thyroid disease | 23 | −0.487 | −1.447 | 0.045 | 0.305 |