Table 7 Association between NLRP3 (Q705K) and CARD8 (C10X) genotypes and poor treatment outcome in all TB patients, EPTB and PTB patients respectively in a co-dominant, model.

From: Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia

Gene (Marker)

Genotype

All Cases

p

PTB

p

EPTB

p

  

OR (95% CI)

 

OR (95% CI)

 

OR (95% CI)

 

NLRP3 (Q705K)

NLRP3

      

rs35829419

CA

3.09 (1.09–8.80)

0.035

3.92 (1.33–11.53)

0.013

—

—

 

AA

—

—

—

—

—

—

CARD8 (C10X)

CARD8

      

rs2043211

AT

1.03 (0.35–3.02)

0.957

1.10 (0.34–3.56)

0.867

0.62 (0.37–10.48)

0.195

 

TT

1.22 (0.30–5.03)

0.781

1.70 (0.39–7.40)

0.481

—

—

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