Table 1 Free and conjugated BAs in the serum of Apoe−/− mice (ng/mL) fed whole lingonberries and their separated soluble and insoluble fractions and the control diets.
Bile acids | Control – Low Fat | Control – High Fat | Whole Lingonberry | Soluble Lingonberrya | Insoluble Lingonberry |
|---|---|---|---|---|---|
Unconjugated | |||||
CA | 99.6 ± 15.0 | 90.7 ± 12.0 | 71.5 ± 7.0 | 70.0 ± 4.8 | 114.0 ± 16.2 |
α-MCA | 13.3 ± 0.8 | 17.2 ± 0.8 | 23.8 ± 3.0††† | 13.0 ± 0.8 | 18.3 ± 1.5 |
β-MCA | 40.3 ± 3.5 | 92.7 ± 12.8††† | 78.7 ± 6.1†† | 54.6 ± 6.7 | 81.6 ± 10.8†† |
ω-MCA | 62.6 ± 4.9 | 100.6 ± 14.2 | 157.0 ± 25.3*†††† | 59.7 ± 2.8 | 64 ± 7.0 |
CDCA | 27.3 ± 0.1 | 29.1 ± 0.4 | 34.5 ± 1.5*†††† | 28.0 ± 0.2 | 32.5 ± 1.3†† |
DCA | 80.4 ± 6.0 | 116.7 ± 7.5 | 62.1 ± 16.0* | 112 ± 6.0 | 110.4 ± 13.0 |
HDCA | 20.9 ± 0.6 | 20.4 ± 0.6 | 26.3 ± 3.4 | 19.7 ± 0.3 | 19.5 ± 0.6 |
UDCA | 22.9 ± 0.7 | 34.6 ± 3.5 | 62.7 ± 11.2*†††† | 24.3 ± 1.5 | 35.0 ± 2.3 |
LCA | <RL | <RL | <RL | <RL | <RL |
Glycine-conjugated | |||||
G-CA | 15.9 ± 0.1 | 16.2 ± 0.1 | 16.5 ± 0.2 | 15.9 ± 0.1 | 16.3 ± 0.2 |
G-LCA | 25.2 ± 0.01 | 25.2 ± 0.01 | 25.2 ± 0.02 | 25.2 ± 0.01 | 25.2 ± 0.02 |
G-CDCA | 19.2 ± 0.2 | 19.0 ± 0.5 | 19.5 ± 0.2 | 19.2 ± 0.6 | 19.7 ± 0.5 |
G-DCA | 18.0 ± 0.01 | 18.2 ± 0.07 | 18.1 ± 0.05 | 18.1 ± 0.06 | 18.1 ± 0.05 |
G-UDCA | 13.5 ± 0.02 | 13.5 ± 0.03 | 13.6 ± 0.01 | 13.6 ± 0.01 | 13.6 ± 0.01 |
Taurine-conjugated | |||||
T-CA | 132.2 ± 15.2 | 175.6 ± 16.7 | 99.8 ± 10.5* | 252.1 ± 31.8†† | 151.0 ± 28.9 |
T-α-MCA | 57.3 ± 6.3 | 207.9 ± 24.8†††† | 182.6 ± 20.7†††† | 163.6 ± 18.0†† | 98.9 ± 8.1** |
T-β-MCA | 30.3 ± 1.6 | 55.2 ± 1.8 | 66.0 ± 7.5††† | 48.2 ± 2.6 | 68.6 ± 10.8††† |
T-UDCA | 43.1 ± 1.6 | 87.1 ± 5.7†††† | 76.3 ± 3.1†††† | 53.1 ± 2.4**** | 46.6 ± 3.3**** |
T-CDCA | 29.0 ± 0.5 | 32.7 ± 1.1 | 30.5 ± 0.9 | 35.9 ± 3.3†† | 31.0 ± 1.2 |
T-DCA | 36.5 ± 1.9 | 38.8 ± 2.1 | 28.6 ± 1.0**† | 36.4 ± 0.4 | 37.4 ± 2.3 |
T-LCA | <RL | <RL | <RL | <RL | <RL |
