Figure 2

(a) Space-time visualization of a self-oscillating cluster, with cells in |x| < 0.15 mm. k_e = 5.0 min⁻¹. (b) A larger cluster of cells with L = 0.375 mm and k_e = 5.0 min⁻¹. (c) Different representation of the simulation in (b), concentration of cAMP is shown in the z axis with equitemporal lines to guide the view. The increase in amplitude towards the cluster edges can be observed (see also Supplementary Video S2). (d) Oscillation period of isolated clusters depending on their size in black line. Cells located in |x| < L and rest of the system empty space, k_e = 5.0 min⁻¹. Red dashed line marks the period of the limit cycle in spaceless (0-D) simulations.